Dr. Lars Leksell 1907-1986

Dr. Lars Leksell was born in Fassberg, Sweden on November 23rd 1907, Lars Leksell completed medical studies at the Karolinska Institute and began his Neurosurgical training in 1935 under Dr. Herbert Olivercrona. Development of electronystagmography and his thesis on muscular control and Gamma Motor Neurons were his early scientific achievements. In 1949, he developed his Arc Centered Stereotactic Frame based on Cartesian coordinate system. In 1951, using the Uppsala University cyclotron, Leksell and the physicist and radiobiologist Borje Larsson, developed the concept of Radiosurgery. Leksell and Larsson first employed proton beams coming from several directions into a small area into the brain, in experiments in animals and in the first treatments of human patients. Thus, he achieved a new non-invasive method of destroying discrete anatomical regions within the brain while minimizing the effect on the surrounding tissues. In 1961 he succeeded Olivercrona as Professor & Chairman of Neurosurgery at Karolinska institute and perused his work on Stereotactic Radiosurgery and refinement of Stereotactic methods. First prototype of Gamma Knife was installed in Sophiahemmet in 1968.

Today, Leksell's technique is used as an effective treatment for many conditions such as arteriovenous malformations, pituitary tumors, acoustic neuromas, craniopharyngiomas, Meningioma, Matastatic and skull base tumors, and primary brain tumors. The Gamma Knife is manufactured by Elekta Instruments, Inc., a Swedish company which manufactures Stereotactic surgery and Radiosurgery equipment, based on the inventions of Lars Leksell. It was founded by him in 1972.


He died peacefully at age of 78 n 1986 while taking a brisk walk in Swiss alps.

  1. Brain Fragment by Dr. Lars Leksell translation Melita Steiner :Radiosurgery baseline and trends Edited by L. Steiner et al Raven Press Ltd 1992
  2. Lars Leksell an Historical Vignette Dan Leksell :Radiosurgery baseline and trends Edited by L. Steiner et al Raven Press Ltd 1992
  3. Sabbatini, R.M.E. A, Brief Biography of Lars Leksell. htm brain & mind .com
What is Gamma Knife ?
Gamma Knife treatment offers new hope for patients with brain tumors, vascular malformations and functional disorders